Week 12 NFL Friday Injury Report: Big Games Coming for Wilson, White, Perine?

This article is part of our Injury Analysis series.

There was no shortage of big, fantasy-relevant injury news this Friday, and that's on top of three starting QB changes earlier in the week (Mike White, Sam Darnold, Kyle Allen). A fourth team, the Rams, declined to name its Week 12 starter after Friday's practice, though most signs point to Bryce Perkins after he took first-team reps throughout the week. That said, John Wolford isn't listed on the final injury report, nor is fellow NFC West quarterback Kyler Murray.

The bottom section here — labelled 'truly questionable' — can be used as a checklist/cheatsheet for Sunday morning and afternoon when inactive lists come out. First, let's see who's definitely in and who's definitely out...

Good to Go 💯

• QB Kyler Murray (hamstring)
• QB John Wolford (neck) 
• RB Aaron Jones (shin) + WRs Allen Lazard (shoulder) & Randall Cobb (illness) + TE Robert Tonyan (illness)
• WR A.J. Brown (illness)
• WR JuJu Smith-Schuster (concussion)
• WR Corey Davis

Ruled Out/Doubtful 🚑 

• QB Matthew Stafford (neck)
• RB Raheem Mostert (D - knee)
• RB Leonard Fournette (D - hip)
• RB Joe Mixon (concussion)
• RB Clyde Edwards-Helaire (IR - ankle)
• WR Mike Williams (ankle)
• WRs Jerry Jeudy (ankle) & KJ Hamler (hamstring)
• WR Rondale Moore (groin)
• WRs Kadarius Toney (hamstring) + Mecole Hardman (IR - groin)
• WR Russell Gage (hamstring)
• WR Dee Eskridge (hand)
• WR Romeo Doubs (ankle)
• WR Hunter Renfrow (IR - oblique) + TE Darren Waller (IR - hamstring)

Key Defensive Players + Offensive Linemen

• CB Greg Newsome (concussion)
• LT Ronnie Stanley (ankle)
• CB Derek Stingley (hamstring)
• S Jaquan Brisker (concussion) + CB Kyler Gordon (concussion)
• DL/OLB Denico Autry (knee)
• CB Kristian Fulton (hamstring) + C Ben Jones (concussion)
• CB Benjamin St-Juste (ankle)
• CB Byron Murphy (back) + OT D.J. Humphries (back)
• C Brian Allen (thumb)
• LB De'Vondre Campbell (knee)

Listed as Questionable - Should Play 👍

• RB Gus Edwards (hamstring) - 1:00 ET
• WR Terrace Marshall (shoulder) - 1 ET
• TE Logan Thomas (ribs/illness) - 1 ET
• DL Jeffery Simmons (ankle) - 1 ET

Truly Questionable 🤔

Early Games

• QB Justin Fields (shoulder) 
• WR Ja'Marr Chase (hip)
• WRs Devin Duvernay (hamstring) & Demarcus Robinson (hip) + TE Isaiah Likely (ankle)
• RB Caleb Huntley (ankle)

Duvernay and Likely were end-of-week additions to the injury report, listed as questionable after limited practices Friday. Robinson, on the other hand, missed practice Friday before being a full participant Friday, i.e., he should be able to play. James Proche and DeSean Jackson (hamstring) could run more routes if Duvernay is out (Jackson is on the practice squad but reportedly was able to practice this week).

Late Afternoon

• RB Josh Jacobs (calf) - 4:05
• WRs Marquise Brown (IR - foot) & Greg Dortch (thumb) - 4:05
• WR Allen Robinson (ankle) + TE Tyler Higbee (knee) - 4:25 
• WR Deebo Samuel (hamstring) - 4:25
• RB Mark Ingram (knee) - 4:25

Zamir White could get his first chance in the lead role if Jacobs is out, with Ameer Abdullah and Brandon Bolden also candidates to pick up some snaps (but mostly on passing downs, presumably). 

For the Cardinals, it's unclear who will take WR snaps besides DeAndre Hopkins, as coach Kliff Kingsbury said earlier this week that Brown will be on a "pitch count" if he plays. Rondale Moore (groin) is already ruled out, and A.J. Green worked ahead of Robbie Anderson last week when the Cards were pressed for depth.

For Robinson and Higbee, I don't really have a read apart from not wanting to roster either of them anyway. The Rams are a mess at QB and along the O-line, and neither Robinson nor Higbee looks like the two-years-ago version of himself.

Deebo seems healthy enough to play, but I'm putting him in this section because the Niners don't necessarily need him this week and might be worried about the hamstring injury lingering (or worsening) if he doesn't rest. Upgrade Brandon Aiyuk and George Kittle (and Jauan Jennings!) if there's word of Samuel being limited or absent Sunday afternoon.

Primetime

• RB Jaylen Warren (hamstring) - MNF

Key Defensive Players + O-Linemen

• DT Vita Vea (foot) - 1 ET
• K Randy Bullock (calf) - 1 ET
• DE Chase Young (knee) - 1 ET
• LT Kolton Miller (shoulder) - 4:05 ET
• S Juan Thornhill (calf) + G Joe Thuney (ankle) - 4:25 ET
• CB Marshon Lattimore (abs) + DEs Marcus Davenport (calf) & Cameron Jordan (eye)
• Ahkello Witherspoon (hamstring) - MNF