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Dre Greenlaw
Set to play in Week 16
Greenlaw said Tuesday that he will be available to suit up in Week 16 against the Dolphins, David Bonilla of 49ers Webzone reports.
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De'Vondre Campbell
Team ready to cut ties
Head coach Kyle Shanahan confirmed Friday that Campbell will not suit up again for the 49ers after refusing to enter Thursday night's game against the Rams, Nick Wagoner of ESPN.com reports.
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Patrick Taylor
Likely to remain backup Week 15
Taylor's expected to remain in a backup role Thursday against the Rams, as sources tell Adam Schefter of ESPN that Isaac Guerendo plans to play despite spraining his foot in Sunday's win over the Bears.
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Isaac Guerendo
Plans to play Thursday
Sources tell Adam Schefter of ESPN that Guerendo plans to play Thursday night against the Rams despite spraining his foot in Sunday's win over the Bears.
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Deebo Samuel
Might get more involved in offense
Coach Kyle Shanahan said in his press conference Tuesday that the 49ers are hoping to get Samuel the ball more often Thursday against the Rams.
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Isaac Guerendo
Week 15 status in jeopardy
Guerendo suffered a foot sprain in a Week 14 win over the Bears that will require further evaluation, Ian Rapoport of NFL Network reports.
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Israel Abanikanda
Likely to debut Week 15
Abanikanda could make his 49ers debut Thursday against the Rams, as coach Kyle Shanahan said after Sunday's 38-13 win over the Bears that Isaac Guerendo has a possible foot sprain, Eric Branch of the San Francisco Chronicle reports.
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Ke'Shawn Vaughn
Could play more Thursday
Vaughn could see a larger role Thursday against the Rams, as coach Kyle Shanahan said after Sunday's 38-13 win over the Bears that Isaac Guerendo has a possible foot sprain, Eric Branch of the San Francisco Chronicle reports.
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Patrick Taylor
Next in line after Guerendo injury
Taylor could get a chance to start Thursday against the Rams, as coach Kyle Shanahan said after Sunday's 38-13 win over the Bears that Isaac Guerendo has a possible foot sprain, Eric Branch of the San Francisco Chronicle reports.
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Nick Bosa
Another absence likely forthcoming
Bosa, who's missed the last two games with hip and oblique injuries, is listed as doubtful for Sunday's game against the Bears, Nick Wagoner of ESPN.com reports.
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Brock Purdy
Set for contentious negotiations?
Purdy could be the next 49ers star player to have contentious extension negotiations, Albert Breer of SI.com speculates.
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Isaac Guerendo
In line for starting job
Guerendo is likely to be the starting running back for the 49ers in Week 14 and beyond with Ian Rapoport of NFL Network reporting that Christian McCaffrey and Jordan Mason have both been placed on IR.
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Christian McCaffrey
May be done for season
McCaffrey may not play again this season after suffering a knee injury in Sunday's loss to the Bills, Ian Rapoport of NFL Network reports.
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Jordan Mason
Back to lead role?
Mason could reclaim the lead role in San Francisco's backfield down the stretch, as Christian McCaffrey suffered a knee injury during Sunday's game against the Bills.
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Jauan Jennings
Getting Purdy back
Jennings and the 49ers' offense will receive a boost for Sunday's night game against the Bills, as quarterback Brock Purdy is expected to return from a one-game absence due to a right shoulder injury, Adam Schefter of ESPN reports.
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Deebo Samuel
Expected to get top QB back Sunday
Samuel and the rest of the 49ers' pass catchers should get a boost in production against the Bills on Suinday, as Brock Purdy is expected to return from a one-game absence due to a right shoulder injury, Nick Wagoner of ESPN.com reports.
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Nick Bosa
Sitting out again Sunday
Bosa has been ruled out for Sunday night's game against the Bills due to his hip and oblique injuries, Nick Wagoner of ESPN.com reports.
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Brock Purdy
Likely back in Week 13
Purdy, who missed the 49ers' Week 12 loss to the Packers with a shoulder injury, is expected to play in Sunday night's showdown against the Bills despite being listed as questionable, Nick Wagoner of ESPN.com reports.
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Dre Greenlaw
Closing in on 2024 debut
Greenlaw is expected to have his 21-day practice window opened this week, Ian Rapoport of NFL Network reports.
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Christian McCaffrey
Could be leaned upon vs. Green Bay
With Brandon Allen starting against the Packers on Sunday due to Brock Purdy being sidelined with a right shoulder injury, Matt Barrows of The Athletic believes the 49ers will be heavily reliant on McCaffrey and the running game.
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Brandon Allen
Drawing Week 12 spot start
Allen, who's made just three regular-season pass attempts since the start of the 2022 campaign, will draw the start for the 49ers against the Packers on Sunday due to Brock Purdy being ruled out because of a shoulder injury, Nick Wagoner of ESPN.com reports.
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George Kittle
Sheds injury tag for Week 12
Kittle, who missed the Week 11 loss to the Seahawks with a hamstring injury, does not carry a designation for Sunday's Week 12 matchup against the Packers, Nick Wagoner of ESPN.com reports.
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Deebo Samuel
Getting fill-in QB on Sunday
Samuel will play with Brandon Allen as his quarterback in Sunday's Week 12 matchup against the Packers after Brock Purdy was ruled out for the game due to a shoulder injury, Nick Wagoner of ESPN.com reports.
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Nick Bosa
Not playing against Packers
Bosa has been ruled out for Sunday's Week 12 matchup against the Packers due to his hip and oblique injuries, Nick Wagoner of ESPN.com reports.
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Brock Purdy
Ruled out for Week 12
Purdy, who's been dealing with shoulder soreness, has been ruled out for Sunday's Week 12 matchup against the Packers, Nick Wagoner of ESPN.com reports.
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