Harry Kane finally broke out of his early season slump, and he'll look to begin a goal streak Saturday against Swansea City.
Danny Rose is one of the best left-backs in the Premier League when fit, but Ben Davies' excellent play this season will make Spurs boss Mauricio Pochettino's job very tough when the former returns from injury.
There could be significant rotation as many players return from international duty, but there's little question that Romelu Lukaku is another top option this weekend.
Paul Pogba broke out last weekend in another dominating win for Manchester United, and a home match against Leicester City keeps him high up the rankings.
Henrikh Mkhitaryan started off his Premier League campaign with two assists in Man United's opener, and a Gameweek 2 match at Swansea City pushes him up the weekly rankings.
The Liverpool attack has a number of strong fantasy options, but RotoWire's Nick Pitner explains why Sadio Mane should be getting more fantasy attention.
Manchester City's match against newly promoted Brighton & Hove Albion pushes plenty of their attackers up the first weekly rankings of the season.
Everton have a number of solid fixtures as the Premier League season winds down, and while Romelu Lukaku will get plenty of fantasy attention, RotoWire's Nick Pitner says don't forget about Tom Davies.
Sadio Mane's injury has opened up a big opening in Liverpool's attack, with 21-year-old Divock Origi ready to take advantage.
After taking some time to break into the squad following his transfer from Schalke, Leroy Sane is flying in the Man City attack, making him an excellent fantasy investment.
Henrikh Mkhitaryan has flourished since getting out of Jose Mourinho's dog house, and another Man United attacker could be following the same path.
Sergio Aguero is widely considered one of the best strikers in the Premier League, but a 19-year-old Brazilian could make him a backup for Man City.
Chelsea extended their winning streak to 11 games this past weekend, and while they have a number of FPL stars, it's all possible thanks to N'Golo Kante's midfield play.
The Man City attack has done just fine under new manager Pep Guardiola, but the back line has really struggled of late, making players like Aleksandar Kolarov very risky fantasy plays.
With Sergio Aguero suspended for the next four Premier League matches, fantasy owners should turn their attention to Kelechi Iheanacho.
Antonio Conte's move to a 3-4-3 formation has done wonders for Chelsea's defense while also opening up Eden Hazard to attack even more than usual.
Xherdan Shaqiri and the Potters are flying of late, and RotoWire's Nick Pitner explains why the good times should keep on rolling in Stoke.
Despite being the second-most popular player in the Premier League's official fantasy game, Nick Pitner warns managers that Kun Aguero may be worth passing on because of his troubles from the penalty spot.
Kevin De Bruyne's hamstring injury is a major blow to the Manchester City midfield, but is Raheem Sterling ready to step into his boots?
Kelechi Iheanacho has starred while filling in for the suspended Sergio Aguero, but with the Argentine back this week, is there enough room for the youngster to keep starting?
After two down performances, Liverpool manhandled the defending champions this past weekend, and Roberto Firmino looks like a top-tier fantasy option once again.
Raheem Sterling struggled in his first season with Manchester City, but he's thriving under new manager Pep Guardiola, making him a legitimate fantasy option.
Sergio Aguero has been the dominant striker in Manchester over the past few seasons, but Zlatan Ibrahimovic is putting up a fight for the top spot.
RotoWire's Nick Pitner breaks down a few key points from Gameweek 1 that can help fantasy owners for the coming weeks, including Jamie Vardy no longer taking penalties for Leicester City.
With Liverpool possibly resting Daniel Sturridge this weekend to prepare for next week's Europa League final, Christian Benteke could be key to winning big on Mondogoal.
Jermain Defoe is doing his best to keep Sunderland in the Premier League, and RotoWire's Nick Pitner thinks he's a great fantasy play this weekend against Chelsea.
Romelu Lukaku has struggled of late, but RotoWire's Nick Pitner explains why he could be a key component of a team trying to win £1 million on Mondogoal.
RotoWire's Nick Pitner breaks down his top plays for Saturday's contests on Mondogoal, when someone could win a cool £1 million.
The Crystal Palace attack appears to be rejuvenated with the full return of Yannick Bolasie, and he could be the key to cashing this weekend on Mondogoal.
RotoWire's Nick Pitner breaks down his top plays for Saturday's contests on Mondogoal, including one that could net someone £1 million.
RotoWire's Nick Pitner breaks down his best XI for Saturday's Perfect Million contest on Mondogoal, including Romelu Lukaku against a suddenly shaky Arsenal defense.
West Ham are vying for a spot in Europe next season, but they'll have their hands full Saturday trying to contain Romelu Lukaku, who has scored in six consecutive games against the Hammers.
Despite losing at Old Trafford on Sunday, Mesut Ozil scored and grabbed his 18th assist in league play, making him a great play Wednesday against Swansea City.
Jamie Vardy has four goals in his last four matches and will be looking to bag his 20th of the season this weekend against Norwich.
With Mondogoal giving away £1 million for the person who can pick the perfect fantasy lineup, RotoWire's Nick Pitner takes his shot for Saturday's contest.
Using Mondogoal's £100 million budget, RotoWire's Nick Pitner explains why it's paramount to pay up for Sergio Aguero.
Using Mondogoal's £100 million budget, RotoWire's Nick Pitner picks the top players for this weekend, including a surging Sergio Aguero.
RotoWire's Nick Pitner uses Mondogoal's £100M budget to select his Best XI for Gameweek 22, highlighted by Harry Kane, who will fire off shots against the Premier League's worst defense.
After scoring in Arsenal's FA Cup win over Sunderland this past weekend, Olivier Giroud now sports 16 goals in 21 starts this season, and he takes the Best XI captain's armband for Week 21.
Diego Costa looks renewed under interim manager Guus Hiddink, and he could continue his fine play Wednesday against West Brom.
Romelu Lukaku has scored 10 goals in his last nine league games, and he's got a great opportunity this weekend to extend his streak.
Looking to bounce back from a surprising 4-0 loss to Southampton on Boxing Day, Arsenal's Petr Cech will try again for the Premier League clean sheet record Monday against Bournemouth.
Romelu Lukaku has found the back of the net in seven consecutive league matches, and he takes the Best XI captain's armband heading into Saturday's match against a struggling Newcastle side.
Romelu Lukaku has scored in seven consecutive matches and will look to extend his streak against Newcastle, who have allowed more goals than all but one team this season.
While many will be focusing on Arsenal v. Man City this weekend, Everton v. Leicester may be the one with the most fireworks thanks to a matchup with the league's top two goal scorers.
Romelu Lukaku has five goals and three assists in eight home matches this season and now gets to face a Leicester side hardly known for its defensive prowess.
With a goal or an assist in nine straight league matches, Mesut Ozil earns the Best XI captain's armband ahead of this weekend's tie with Aston Villa.
Romelu Lukaku has scored in six consecutive games and is arguably the best fantasy striker this weekend.
Fresh off his record-setting performance against Manchester United last weekend, Jamie Vardy holds onto the Best XI captain's armband for his matchup against Swansea City.