With Shane Larkin and Efes needing a win and Fenerbahce trying to lock up a playoff spot, Thursday's matchup in Istanbul has the makings of an instant classic.
Eternal rivals will face off Friday, as Panathinaikos hits the road to take on Shaquielle McKissic and first-place Olympiacos.
With a number of his teammates unavailable, it could be another big night for Virtus Bologna's Marco Belinelli.
Facundo Campazzo and Red Star face off against Valencia in one of the four games set to be played Wednesday.
Mathias Lessort and Partizan will host Barcelona and punctuate play on the first day of the final double-game week of the season.
Five more games will be played Friday, and in the first one up, Achille Polonara and Zalgiris will face off against Fenerbahce.
Road wins have been tough to come by for Maccabi, but they will go for one Thursday, and a red-hot Wade Baldwin will help lead the way.
Bragging rights will be on the line Friday when Andreas Obst and Bayern square off against German rival ALBA.
Nigel Hayes-Davis and Fenerbahce hit the road to take on Valencia in one of the seven games set to be played Thursday.
Jan Vesely will face his former club Friday as he and Barcelona travel to Istanbul to take on Fenerbahce.
The second Round of the week gets underway Thursday, and the action begins with a matchup between Virtus Bologna and Christ Koumadje's ALBA club.
Will Clyburn and Efes will look to maintain the momentum when they take on Red Star in one of the three games set to be played Wednesday.
A big night from Markus Howard would provide a big boost as he and Baskonia try to knock off first-place Real Madrid on the first day of the double-game week.
A pivotal matchup featuring Jared Harper's Valencia club and Baskonia headlines a four-game Friday.
All eyes will be on the backcourt when Jordan Loyd and Monaco square off against Maccabi on Thursday.
Thomas Walkup and Olympiacos take on Valencia in one of the five games set to be played Friday.
The EuroLeague break is over, and fantasy contests resume Thursday. Find out why Milan's Shabazz Napier should occupy a spot in your lineups.
Dee Bost and ASVEL head to the Principality to take on Monaco and kick off the final day of play before the mid-February break.