Although he's yet to have official results from an MRI, multiple reports have indicated that Cameron Meredith likely tore his ACL, and possibly his MCL as well, in Sunday's matchup against the Titans. This is potentially a huge blow to Chicago's passing attack, as he was slated to be the team's top receiving option. The most likely player to take over his spot is Markus Wheaton, but that's if he's able to return from his finger injury. During Sunday's game, Deonte Thompson filled in as an outside receiver. Should Wheaton seize the role, he could have value as a WR4/5. In addition, this injury potentially takes away some of the small upside that Mike Glennon or Mitch Trubisky have.

• Stop the presses! The Browns have named DeShone Kizer as their starting quarterback for Week 1. Although he completed just six of 18 passes for 93 yards and an INT in Saturday's preseason game, the coaching staff doesn't have any compelling options at QB to keep them from getting the rookie some game action. Fantasy owners should take note, as we've seen plenty of times in the past that a QB doesn't have to be a good passer to be a strong fantasy option if he has the ability to run the football. He immediately should be considered a viable QB option, and he has potential upside to be a matchup starter based on his rushing ability.
• Hardly anyone is talking about him in the fantasy community, but Andre Holmes had the most snaps of any Bills skill-position players in Saturday's game. Although he caught just a single pass for nine yards, most of the game was played without Tyrod Taylor (concussion). The fact that Holmes played so many snaps may indicate that the team recognizes that he's the only true deep threat on the roster, and when Taylor's healthy, he'll be able to take advantage of Holmes' strengths. He's going undrafted in many leagues, but if you're looking for a lottery ticket at the end of the draft, he could be worth a flyer.
• Back to the Bears preseason game, both Glennon and Trubisky completed over 66% of their passes while throwing a TD pass. The one thing that won't be reflected in the box score is that Trubisky threw a sure INT, but the defender dropped the pass. Regardless, it still appears that Glennon's on track to open the season under center, but there's also an excellent chance that Trubisky gets his shot to lead the team at some point during the season. Neither profiles as more than a QB2, and both are being viewed accordingly in most fantasy drafts.
• Also, the Meredith injury will lead many fantasy managers to wonder how this may affect Jordan Howard, and it would seem as if it should have little to no impact on his fantasy value. During Howard's breakout rookie season, the team had a number of backup QBs in the lineup and they played the last four games of the season without Alshon Jeffery, so this won't be the first time that he'll be facing defenses that will be making him their primary focus. Not only did he prove to be an excellent runner last year, he's also running behind a solid and cohesive offensive line. I still recommend drafting him with confidence.
• In other preseason action, Jordan Reed made his season debut after missing time with a toe injury. Although he caught just two passes for 14 yards, all that really matters is that he's back on the field. Everyone knows the risk they take when selecting him in fantasy drafts due to his extensive injury history, but his tantalizing upside is what has him being drafted as one of the first TEs off the board with an ADP of 51. Fantasy managers are typically forced to take a stand on him based on their level of risk aversion. Personally, I'm more troubled with the concussion history than the foot injury, as one hit to the head could put him out for an extended time.
• In the same contest, Rob Kelley had 10 carries for 57 yards and a TD while rookie Samaje Perine ran the ball five times for 5 yards with Kelley spending most of his time with the first-team offense. Based on the reliability the organization had with Kelley based on last year's performance, it doesn't seem that the Perine's done enough to overtake the starting job. However, this could be a fluid situation throughout the season, and there's no guarantee who'll be the leader in carries for Washington when the season's over. Both RBs are being selected in fantasy drafts, but those who need points from the position early in the season may be better off going with Kelley, while those who are willing to wait for potential production may be inclined to draft Perine. For reference, Kelley's ADP is 102 while Perine's is 128.
• Moving to Cincinnati, Jeremy Hill and Joe Mixon continued to share first-team reps in their matchup with the Redskins. Mixon was slightly more impressive as he carried the ball eight times for 31 yards while Hill carried five times for 15 yards, but scored a touchdown. In addition, Hill left the game with an ankle injury, though no updates been given as to the severity of the injury. It also should be noted that Mixon lost a fumble, but the issue was on the exchange from the QB and wasn't a case where he lost the ball by being hit. At this point, it's anyone's guess as to how Marvin Lewis chooses to handle this backfield, but based on ADP, fantasy managers are putting much more confidence in the rookie. We've all seen Hill be ordinary over the last two seasons, so it's a good bet that the rookie will eventually take hold of this job. Those who guess correctly may actually be getting Mixon at a discount, as his ADP has dropped a bit to 45 over the last few weeks.